1
as in rebellious
given to resisting authority or another's control
refractory players will be ejected from the game
Synonyms & Similar Words
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Antonyms & Near Antonyms
2
as in stubborn
given to resisting control or discipline by others
believing that rules are only for other people, he's been refractory virtually his entire life
Synonyms & Similar Words
Antonyms & Near Antonyms
Example Sentences
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Recent Examples of refractory
This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA.
—
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
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These two regions are no longer promising New World upstarts or rebellious outposts of Bordeaux.—
Jessica Dupuy,
Forbes.com,
21 May 2025
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Meanwhile, Paul finds himself in a work crisis that puts the lifestyle of Julie and their rebellious son Russ (Simon Webster) in jeopardy, leading Julie back to the dopey sweetness of Carey.—
Esther Zuckerman,
IndieWire,
19 May 2025
Adjective
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Jet fuel rolled down the street and the smell of it lingered in the air while authorities worked to extinguish one stubborn car fire that sent smoke billowing up.—
John Hanna,
Chicago Tribune,
22 May 2025
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Of course, stubborn coach Tom Thibodeau went with his only play, a Jalen Brunson iso, while the starters huffed and puffed from playing nearly the entire game.—
Alphonse Pierre,
Pitchfork,
22 May 2025
Adjective
-
President Trump met with former rebel leader turned new president of Syria, Ahmed al-Sharaa.—
ABC News,
ABC News,
18 May 2025
-
Incidents of violence by rebel groups fell from 1,936 in 2010 to 374 in 2024, according to data from the home ministry.—
Rhea Mogul,
CNN Money,
15 May 2025
Adjective
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In response, these recalcitrant members of Congress simply refused to adopt must-pass federal reapportionment legislation.—
Made by History,
Time,
2 Apr. 2025
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Among Congressional Republicans, Paul has been more recalcitrant than most.—
Eric Cortellessa,
TIME,
18 Mar. 2025
Adjective
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Bowser’s shifting response on immigration matters is one of a number of ways the mayor, a leading figure in the Democratic resistance during Trump’s first term, is now striking a less defiant tone.—
Catherine E. Shoichet,
CNN Money,
28 May 2025
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Moxley took out Nightingale to massive heat, and Omega hit a snap-dragon suplex on a defiant Marina Shafir.—
Alfred Konuwa,
Forbes.com,
26 May 2025
Adjective
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The issue of a ceasefire is where the intractable differences are clearest.—
Clare Sebastian,
CNN Money,
16 May 2025
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Unemployment fueling instability While African political campaigns often make note of persistently high rates of youth unemployment, the policy priorities of governments across the continent have seemingly failed to fix this intractable problem.—
Richard Aidoo,
The Conversation,
10 Apr. 2025
Adjective
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Research shows that people under stress are more likely to give up, but only when the situation feels uncontrollable.—
Mark Travers,
Forbes.com,
20 May 2025
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Entire neighborhoods are retrofitted with clear glass domes that activate during extreme rainstorms and uncontrollable wildfires.—
Lovia Gyarkye,
HollywoodReporter,
16 May 2025
Adjective
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In fact, too much change at once becomes unmanageable noise.—
Kathleen Walch,
Forbes.com,
23 May 2025
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Freedom Debt Relief offers a five-step program to alleviate unmanageable debt without charging sign-up fees.—
Jason Phillips,
USA Today,
17 May 2025
Cite this Entry
“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 3 Jun. 2025.
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