How to Use refractory in a Sentence

refractory

adjective
  • Made with refractory material like that found in faux fireplace logs, the spooky stoneware skulls are fireproof and lightweight.
    Taysha Murtaugh, Country Living, 10 Oct. 2018
  • Soon Maggie seems to be channeling him, both in her refractory behavior and in her strange, scrawled paintings.
    Sam Sacks, WSJ, 18 May 2018
  • However, there is some concern regarding the safety of PPI treatment, as well as the fact that a subset of patients are refractory.
    Joshua Cohen, Forbes, 1 June 2022
  • It’s being used in patients with relapsed and refractory multiple myeloma, a cancer of the bone marrow.
    Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • This response lasts for about 10 minutes, after which the cat becomes refractory to catnip’s effects for roughly 30 minutes.
    Kate Wong, Scientific American, 1 Oct. 2018
  • One featured patients with refractory celiac disease type 2, the most severe form of celiac disease.
    Sumathi Reddy, WSJ, 16 Apr. 2018
  • Cinematographer Yves Bélanger was having a fair amount of fun with fish-eye lenses, refractory visual effects, and askew angles.
    Roxana Hadadi, Vulture, 15 Sep. 2021
  • Magneco/Metrel was founded in 1981 and specializes in refractory products for aluminum, brick, ceramic, glass, iron and steel.
    William Thornton | Wthornton@al.com, al, 1 Mar. 2023
  • The ketogenic diet was developed nearly 100 years ago to reduce seizures in children with refractory epilepsy.
    Bradley J. Fikes, sandiegouniontribune.com, 6 May 2017
  • For instance, determining whether a heart attack needs to be urgently catheterized depends in part on if a patient’s chest pain is refractory to medical treatment.
    Abraar Karan, BostonGlobe.com, 9 Aug. 2019
  • Global biotech Oncopeptides won approval for Pepaxto, its drug to treat adults with relapsed or refractory multiple myeloma.
    BostonGlobe.com, 31 Mar. 2021
  • These fractious workplace relationships aren’t so much the fault of refractory unions or exploitative bosses, as the inevitable outcome of poor geology.
    Washington Post, 12 May 2019
  • The 9% rise can primarily be attributed to the announcement of positive interim data from a phase one study for patients with relapsed or refractory B-cell lymphoma.
    Trefis Team, Forbes, 30 Mar. 2021
  • But 5% of heart failure remains refractory to medical treatment, and in these patients palliative care has been shown to improve patient satisfaction and decrease costs.
    Marc Siegel, WSJ, 16 Apr. 2018
  • Another way to reduce what reaches the ground is to substitute refractory materials such as titanium and steel, used to make things like fuel tanks and fly wheels, with substances such as aluminium and graphite epoxy that vaporise more easily.
    The Economist, 10 Aug. 2019
  • Interim results from two Phase 3 studies show the ability of ibrexafungerp to combat refractory fungal infections in a hospital setting.
    Joshua Cohen, Forbes, 6 July 2022
  • And since other medical treatments for refractory endometriosis carry other risks, that surgical diagnosis is important for confirming the cause of the pain before those other options are tried.
    Perri Klass, New York Times, 3 Feb. 2020
  • These trials routinely focus on those cancers, such as multiple myeloma and refractory colon cancer, which have resisted standard therapies.
    Dallas News, 4 Sep. 2018
  • At an outpatient clinic, Tawfik treats rare and refractory types of pain usually associated with surgery or injury, such as chronic neuropathic pain and complex regional pain syndrome.
    Troy Farah, Scientific American, 30 Sep. 2021
  • Many less attractive traits are also recorded: Charles could be uncommunicative and dilatory, evasive and mendacious, refractory, vindictive, obstinate, even outright wicked, though self-delusive about the motives of others.
    R.j.w. Evans, The New York Review of Books, 11 June 2020
  • All of these participants were also taking opioids, but still experiencing refractory pain.
    Sarah Jacoby, SELF, 21 Sep. 2017
  • One advancement has come in the ability to manufacture refractory metals, which are extraordinarily resistant to heating.
    Eric Berger, Ars Technica, 15 June 2020
  • Work is also progressing to explore bone marrow transplants as a novel pathway to treating debilitating conditions like refractory inflammatory bowel disease (IBD).
    Scientific American, 24 Mar. 2020
  • Made with refractory material like that found in faux fireplace logs, the spooky stoneware skulls are fireproof and lightweight.
    Taysha Murtaugh, Country Living, 10 Oct. 2018
  • Soon Maggie seems to be channeling him, both in her refractory behavior and in her strange, scrawled paintings.
    Sam Sacks, WSJ, 18 May 2018
  • However, there is some concern regarding the safety of PPI treatment, as well as the fact that a subset of patients are refractory.
    Joshua Cohen, Forbes, 1 June 2022
  • It’s being used in patients with relapsed and refractory multiple myeloma, a cancer of the bone marrow.
    Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • This response lasts for about 10 minutes, after which the cat becomes refractory to catnip’s effects for roughly 30 minutes.
    Kate Wong, Scientific American, 1 Oct. 2018
  • One featured patients with refractory celiac disease type 2, the most severe form of celiac disease.
    Sumathi Reddy, WSJ, 16 Apr. 2018
  • Cinematographer Yves Bélanger was having a fair amount of fun with fish-eye lenses, refractory visual effects, and askew angles.
    Roxana Hadadi, Vulture, 15 Sep. 2021

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'refractory.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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