FIRST-LINE Synonyms: 24 Similar and Opposite Words

first-line

adjective

ˈfərst-ˈlīn

as in selected

singled out from a number or group as more to one's liking surgery is usually not considered a first-line treatment for this type of cancer

Synonyms & Similar Words

Relevance

Antonyms & Near Antonyms

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.

Recent Examples of first-line Right now, chemotherapy is still recommended as a first-line treatment for patients with advanced pancreatic cancer. —

Erika Edwards, NBC news, 31 May 2026 Richman, the Citizen Oversight Board member, does not believe first-line supervisors are equipped to thoroughly review misconduct allegations and make informed decisions on what warrants further review. —

Shelly Bradbury, Denver Post, 29 May 2026 Doctors typically start with neuropathic pain medications like gabapentin, which is a common first-line option, along with behavioral support and complementary approaches like acupuncture. —

Helen Carefoot, Flow Space, 27 May 2026 These precede adaptive responses, acting as first-line, non-specific defenses against germs and injury. —

Beth Mole, ArsTechnica, 15 May 2026 See All Example Sentences for first-line

Recent Examples of Synonyms for first-line

Adjective

These pre-selected fighter pilots and their families moved into their apartments during the summer of 1960 after residing at the Frunze Central Airfield in Moscow.

— Jeff Spry, Space.com, 27 May 2026
Viewers can earn in-game gear, weapons and other rare items by watching selected streamers who are playing Tarkov.

— Mike Stubbs, Forbes.com, 25 May 2026