: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line

Examples of first-line in a Sentence

surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This first-line treatment for dysphonia helps to weaken the vocal folds that contract abnormally with this condition. Indu Subramanian, The Conversation, 1 May 2025 After first-line center Robin Sapousek got injured at the World Juniors, Reschny became Victoria’s 1C at 16. Scott Wheeler, New York Times, 1 May 2025 If results remain strong, immunotherapy could become a standard first-line option for many patients, reshaping cancer care for years to come. Mohammed Soliman, MSNBC Newsweek, 28 Apr. 2025 Until now, levodopa has been the standard first-line treatment for Parkinson’s patients. Melissa Rudy, FOXNews.com, 18 Apr. 2025 See All Example Sentences for first-line

Word History

First Known Use

1919, in the meaning defined above

Time Traveler
The first known use of first-line was in 1919

Browse Nearby Words

Cite this Entry

“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 13 May. 2025.

Medical Definition

first-line

adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
Last Updated: - Updated example sentences
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