How to Use first-line in a Sentence

first-line

adjective
  • Then the Wings lost Vrana and first-line winger Tyler Bertuzzi, forcing some new looks.
    Helene St. James, Detroit Free Press, 28 Apr. 2023
  • This is the first first-line FDA approval for a drug treating this cancer in over 20 years.
    Katie Jennings, Forbes, 19 Apr. 2023
  • It has been used as a first-line treatment in Canada and parts and Europe for more than 40 years.
    Claire Bugos, Verywell Health, 8 May 2024
  • Metformin is a first-line treatment for type 2 diabetes in adults and children aged 10 and above.
    Nick Blackmer, Verywell Health, 15 Apr. 2024
  • Nearly 70% of adults in the U.S. use over-the-counter medications as a first-line response for treating cold and flu symptoms.
    Macarius Mwinisungee Donneyong, Fortune Well, 21 Apr. 2023
  • Since the 1930s, EEGs have been the first-line method for recording the sleeping brain’s electrical activity.
    Lucy Tu, Smithsonian Magazine, 24 Mar. 2023
  • Corticosteroids are one of the first-line treatments for lupus.
    Anne Harding, Health, 19 Apr. 2023
  • Among the drugs in shortage is carboplatin, a chemotherapy agent used as a first-line treatment for a number of cancers.
    Marina Kopf, NBC News, 26 May 2023
  • Police also used a liquid known as Bluestar that is meant to be a first-line method of picking up blood stains not visible to the human eye.
    Jessica Garrison, Los Angeles Times, 1 June 2024
  • Providers first try first-line drugs, which are known to be the most effective (before the development of antimicrobial resistance) and the least toxic.
    Erin Prater, Fortune Well, 17 Jan. 2024
  • The medications can be used along previous first-line treatments for migraine.
    Syeda Khaula Saad, Verywell Health, 3 Apr. 2024
  • Sleep medications—either over-the-counter or prescription—are not recommended as a first-line treatment, and they're not meant to be taken long-term.
    Amanda MacMillan, Health, 6 Aug. 2023
  • Companies usually need such a system to operate as a first-line customer support bot for end users.
    Stoyan Mitov, Forbes, 1 Mar. 2024
  • That includes junior first-line winger Jack Stanius and top-tier defenseman Blake Eckerle.
    Jace Frederick, Twin Cities, 6 Mar. 2024
  • Companies have started trimming back on employee benefits over the past few years as a first-line cost-cutting measure.
    Paige McGlauflin, Fortune, 8 Feb. 2024
  • Just a week ago, only Brodin and Zuccarello were sidelined from the group that includes two first-line wings, the most experienced pair of blue-liners and their primary netminder.
    Dave Campbell, USA TODAY, 5 Jan. 2024
  • Bergeron was still, undeniably, a first-line center, a defensive force, and the fulcrum of everything coach Jim Montgomery wanted and needed the Bruins to do.
    Globe Staff, BostonGlobe.com, 28 July 2023
  • Semaglutide safety concerns Public concerns about the safety of the drug may also be an obstacle to its wider adoption as a first-line treatment against obesity.
    Elizabeth Napolitano, CBS News, 8 Aug. 2023
  • There was also a tripling of the number of cases resistant to echinocandins, the first-line treatment for Candida auris infections, according to data from the CDC.
    Faith Karimi, CNN, 21 Mar. 2023
  • While the recent trial showed promising evidence that Nexletol could have a role in high cholesterol treatment, statins still have the longest track record, so providers will probably keep using them as first-line treatment.
    Nick Blackmer, Verywell Health, 22 Mar. 2023
  • Multiple states moved to create new poll worker protections this year, and in recent months a handful have moved to further incentivize the people many view as the first-line defense of democracy in the United States.
    Phillip M. Bailey, USA TODAY, 26 July 2023
  • Doxycycline is already the first-line treatment for chlamydia and is an alternative treatment for syphilis in those with a severe penicillin allergy.
    Gabrielle M. Etzel, Washington Examiner, 2 Oct. 2023
  • Public health officials urged doctors to be on the lookout for ringworm infections, also known as tinea, that do not respond to traditional first-line treatments.
    Sarah Kuta, Smithsonian Magazine, 17 May 2023
  • While penicillin is the standard first-line treatment for syphilis, Tilghman said there is plenty of evidence that doxycycline is very effective, though it’s generally taken in oral form — two pills daily.
    Paul Sisson, San Diego Union-Tribune, 1 July 2023
  • Although laxatives can treat constipation, healthcare providers don't always recommend them as a first-line treatment.
    Stephanie Brown, Verywell Health, 18 Sep. 2023
  • Also, those with atopic dermatitis who do not respond to first-line treatments, such as gentle moisturizers or topical steroids, receive light therapy.
    Karen Pallarito, Health, 18 Dec. 2023
  • Cutting out just one teaspoon of salt from your diet each day can significantly lower blood pressure as good as a first-line medication for hypertension, new research shows.
    Lauren Manaker Ms, Rdn, Health, 23 Nov. 2023
  • If depression fails to respond to first-line treatments, providers may suggest other medications such as esketamine, Carpenter said.
    Sandee Lamotte, CNN, 17 Feb. 2023
  • Your first-line defense Doctors recommend first trying to limit your exposure to whatever is triggering an allergic response — for example, tree pollen in the spring.
    Nina Agrawal, San Diego Union-Tribune, 2 Apr. 2024
  • In addition, if there are true vitamin deficiencies, diet and supplements should be a first-line intervention.
    Sarah Anzlovar, Ms, Verywell Health, 15 May 2023

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'first-line.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Last Updated: