How to Use first-line in a Sentence

first-line

adjective

• Then the Wings lost Vrana and first-line winger Tyler Bertuzzi, forcing some new looks.
  — Helene St. James, Detroit Free Press, 28 Apr. 2023
• This is the first first-line FDA approval for a drug treating this cancer in over 20 years.
  — Katie Jennings, Forbes, 19 Apr. 2023
• It has been used as a first-line treatment in Canada and parts and Europe for more than 40 years.
  — Claire Bugos, Verywell Health, 8 May 2024
• The over-the-counter analgesic, sold as Tylenol or Panadol among other brand names, is the standard, first-line treatment for pain and fever.
  — New Atlas, 15 Dec. 2024
• There’s more consistent offence in his game (eight points in 10 games) as their new first-line right winger.
  — Joshua Kloke, The Athletic, 1 Jan. 2025
• Metformin is a first-line treatment for type 2 diabetes in adults and children aged 10 and above.
  — Nick Blackmer, Verywell Health, 15 Apr. 2024
• Nearly 70% of adults in the U.S. use over-the-counter medications as a first-line response for treating cold and flu symptoms.
  — Macarius Mwinisungee Donneyong, Fortune Well, 21 Apr. 2023
• Since the 1930s, EEGs have been the first-line method for recording the sleeping brain’s electrical activity.
  — Lucy Tu, Smithsonian Magazine, 24 Mar. 2023
• Corticosteroids are one of the first-line treatments for lupus.
  — Anne Harding, Health, 19 Apr. 2023
• The 29-year-old is a dynamic top-six forward with first-line talent and a second-line history.
  — Murat Ates, The Athletic, 20 Feb. 2025
• Among the drugs in shortage is carboplatin, a chemotherapy agent used as a first-line treatment for a number of cancers.
  — Marina Kopf, NBC News, 26 May 2023
• Police also used a liquid known as Bluestar that is meant to be a first-line method of picking up blood stains not visible to the human eye.
  — Jessica Garrison, Los Angeles Times, 1 June 2024
• While beta-blockers used to be a first-line treatment for hypertension, their role has changed in recent years.
  — Ayesha Gulzar, Verywell Health, 18 July 2024
• More comfortable in the middle, but that he’s being asked to be first-line center at times says more about the organization’s needs.
  — Fluto Shinzawa, The Athletic, 7 Jan. 2025
• Clomid and letrozole are the first-line fertility treatments for people with PCOS.
  — Rachel Gurevich, Parents, 30 July 2024
• Providers first try first-line drugs, which are known to be the most effective (before the development of antimicrobial resistance) and the least toxic.
  — Erin Prater, Fortune Well, 17 Jan. 2024
• The medications can be used along previous first-line treatments for migraine.
  — Syeda Khaula Saad, Verywell Health, 3 Apr. 2024
• Sleep medications—either over-the-counter or prescription—are not recommended as a first-line treatment, and they're not meant to be taken long-term.
  — Amanda MacMillan, Health, 6 Aug. 2023
• Companies usually need such a system to operate as a first-line customer support bot for end users.
  — Stoyan Mitov, Forbes, 1 Mar. 2024
• That includes junior first-line winger Jack Stanius and top-tier defenseman Blake Eckerle.
  — Jace Frederick, Twin Cities, 6 Mar. 2024
• Creating a better sleep environment: Going to bed at the same time every night and keeping your bedroom cool, dark, and quiet are often the first-line ways to improve sleep.
  — Carley Millhone, Health, 10 Oct. 2024
• Companies have started trimming back on employee benefits over the past few years as a first-line cost-cutting measure.
  — Paige McGlauflin, Fortune, 8 Feb. 2024
• Just a week ago, only Brodin and Zuccarello were sidelined from the group that includes two first-line wings, the most experienced pair of blue-liners and their primary netminder.
  — Dave Campbell, USA TODAY, 5 Jan. 2024
• Bergeron was still, undeniably, a first-line center, a defensive force, and the fulcrum of everything coach Jim Montgomery wanted and needed the Bruins to do.
  — Globe Staff, BostonGlobe.com, 28 July 2023
• Semaglutide safety concerns Public concerns about the safety of the drug may also be an obstacle to its wider adoption as a first-line treatment against obesity.
  — Elizabeth Napolitano, CBS News, 8 Aug. 2023
• There was also a tripling of the number of cases resistant to echinocandins, the first-line treatment for Candida auris infections, according to data from the CDC.
  — Faith Karimi, CNN, 21 Mar. 2023
• While the recent trial showed promising evidence that Nexletol could have a role in high cholesterol treatment, statins still have the longest track record, so providers will probably keep using them as first-line treatment.
  — Nick Blackmer, Verywell Health, 22 Mar. 2023
• Multiple states moved to create new poll worker protections this year, and in recent months a handful have moved to further incentivize the people many view as the first-line defense of democracy in the United States.
  — Phillip M. Bailey, USA TODAY, 26 July 2023
• Doxycycline is already the first-line treatment for chlamydia and is an alternative treatment for syphilis in those with a severe penicillin allergy.
  — Gabrielle M. Etzel, Washington Examiner, 2 Oct. 2023
• Stimulant medications are considered the first-line treatment for ADHD for some very good reasons.
  — Alison Escalante, Forbes, 22 Jan. 2025