1
as in potential
the basic elements from which something can be developed
many thought that the mayor's speech lacked substance because specific proposals for solving the city's problems were few
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2
as in essence
the quality or qualities that make a thing what it is
tireless caring and nurturing that was the very substance of maternal love
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3
as in wealth
the total of one's money and property
measure the worth of a person not by his earthly substance but by his good deeds
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4
as in object
one that has a real and independent existence
the question of whether the soul is a substance entirely independent of the body
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Merriam-Webster unabridged
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