resistance

1 of 2

noun

re·​sis·​tance ri-ˈzi-stən(t)s 

plural resistances

1

a

: an act or instance of resisting : opposition

b

: a means of resisting

2

: the power or capacity to resist: such as

a

: the inherent ability of an organism to resist harmful influences (such as disease, toxic agents, or infection)

b

: the capacity of a species or strain of microorganism to survive exposure to a toxic agent (such as a drug) formerly effective against it

3

: an opposing or impeding force

4

a

: the opposition offered by a body or substance to the passage through it of a steady electric current

b

: a source of resistance

5

: a psychological defense mechanism wherein a patient rejects, denies, or otherwise opposes the therapeutic efforts of a psychotherapist

6

often capitalized : an underground organization of a conquered or nearly conquered country engaging in sabotage and secret operations against occupation forces and collaborators

resistance

2 of 2

adjective

: of, relating to, or being exercise involving pushing or pulling against a source of resistance (such as a weight) to increase strength

resistance training

Synonyms

Noun

• defiance
• opposition

Examples of resistance in a Sentence

Noun

They have shown a stubborn resistance to change.

The troops met heavy resistance as they approached the city.

The paint shows good weather resistance.

Over time the patient could develop a resistance to the drug.

Recent Examples on the Web

Noun

The resistance against digital regulation predates the Trump administration. —Camille Grenier, The Conversation, 21 Mar. 2025

As Frederick Douglass noted in a June 1854 newspaper editorial, however, many Americans praised Henry’s phrase and the violent rebellion against British oppression while simultaneously decrying violent resistance to slavery. —Cassandra Good, Smithsonian Magazine, 21 Mar. 2025

Energy Transfer, the operator of the Dakota Access Pipeline, accused Greenpeace USA and International of playing a central role in organizing the resistance to the pipeline at Standing Rock in 2016 and 2017. —Simmone Shah, TIME, 21 Mar. 2025

Yet contemporary audiences are demonstrating unprecedented resistance to these traditional approaches. —James Nord, Forbes, 20 Mar. 2025

Word History

First Known Use

Noun

14th century, in the meaning defined at sense 1a

Adjective

1956, in the meaning defined above

Phrases Containing resistance

• cross-resistance
• insulin resistance
• insulin resistance syndrome
• offered no resistance
• offer resistance
• passive resistance
• take/follow the path/line of least resistance

Rhymes for resistance

• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance
• magnetoresistance

Kids Definition

resistance

noun

re·​sis·​tance

ri-ˈzis-tən(t)s

1

a

: an act or instance of resisting : opposition

b

: a method of resisting

2

: the ability to resist

the body's resistance to disease

3

: an opposing or slowing force

4

: the opposition offered by a body or substance to the passage through it of a steady electric current

5

: a source of resistance

6

often capitalized : a secret organization in a conquered or nearly conquered country fighting against enemy forces

Medical Definition

resistance

noun

re·​sis·​tance ri-ˈzis-tən(t)s 

1

a

: power or capacity to resist

especially : the inherent ability of an organism to resist harmful influences (as disease, toxic agents, or infection)

b

: the capacity of a species or strain of microorganism to survive exposure to a toxic agent (as a drug) formerly effective against it due to genetic mutation and selection for and accumulation of genes conferring protection from the agent especially as a result of overuse of the agent which selectively destroys individual microorganisms lacking the protective genes

2

a

: the opposition offered by a body to the passage through it of a steady electric current

b

: opposition or impediment to the flow of a fluid (as blood or respiratory gases) through one or more passages see vascular resistance

3

: a psychological defense mechanism wherein a psychoanalysis patient rejects, denies, or otherwise opposes therapeutic efforts by the analyst