insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Vitamin D Some evidence suggests that vitamin D deficiency could contribute to insulin resistance and diabetes associated with PCOS. —Emmanuella Ogbonna, Health, 20 June 2025

Linked to obesity, insulin resistance and a fatty liver. —Jesse Pines, Forbes.com, 17 June 2025

After 12 months, the people who got hookworms had lower insulin resistance and reduced fasting blood sugar levels. —Smithsonian Magazine, 12 June 2025

Liquid sugars are absorbed quickly and overwhelm the liver, triggering insulin resistance and increasing diabetes risk over time. —Emily Kay Votruba, EverydayHealth.com, 9 June 2025

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes