annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
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The hydrogen leaks and unrelated helium blockages stalled the flight for two months, coming on top of years of vexing delays and cost overruns.—Marcia Dunn, Chicago Tribune, 2 Apr. 2026 The judging is vexing and perplexing.—Rebecca Alter, Vulture, 28 Mar. 2026 This one is vexing, as it's gone from AI early mover, thanks to its prescient partnership with OpenAI, to a laggard.—Kevin Stankiewicz, CNBC, 27 Mar. 2026 Siblings are rich terrain for fiction precisely because they are so vexed—a pressure point where the imperative to create a singular hero meets the desire to imagine new forms of connection.—Christine Smallwood, Harpers Magazine, 24 Mar. 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way