1
as in adultery
lack of faithfulness especially to one's husband or wife
infidelity can lead to divorce
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2
as in betrayal
the act or fact of violating the trust or confidence of another
the one thing that the political boss will not forgive is infidelity
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3
as in misconduct
a sexual encounter or relationship between a married person and someone other than their spouse
had known about his wife's infidelities for years
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Merriam-Webster unabridged
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