cortex

noun

cor·​tex ˈkȯr-ˌteks 

plural cortices ˈkȯr-tə-ˌsēz  also cortexes

1

a(1)

: the outer or superficial part of an organ or bodily structure (such as the kidney, adrenal gland, or cerebellum or a bone)

especially : cerebral cortex

(2)

: the proteinaceous usually pigmented layer of a hair below the cuticle

b

: the outer part of some organisms (such as paramecia)

2

: a plant bark or rind (such as cinchona) used medicinally

3

a

: the typically parenchymatous layer of tissue external to the vascular tissue and internal to the corky or epidermal tissues of a green plant

broadly : all tissues external to the xylem

b

: an outer or investing layer of various algae, lichens, or fungi

Examples of cortex in a Sentence

Recent Examples on the Web

The first collection features eight products that focus on the scalp, cortex and cuticle, addressing frizz, dryness and damage. —Daniela Avila, People.com, 5 Aug. 2025

Her chip, implanted into her motor cortex, reads brain signals and sends them to a computer. —Kurt Knutsson, FOXNews.com, 1 Aug. 2025

For that reason, all eight products in the line—which range from $32 to $42 and include a mask, leave-in treatment, and the aforementioned curl cream—take a three-pronged approach to hair care by targeting the scalp, inner cortex, and cuticle. —Dianna Singh, Allure, 10 June 2025

For more than a decade, my work as a neuroscientist has focused on the auditory cortex. —Hysell V. Oviedo, The Conversation, 4 June 2025

Word History

Etymology

Latin cortic-, cortex bark — more at cuirass

First Known Use

circa 1676, in the meaning defined at sense 1a(1)

Phrases Containing cortex

• cerebral cortex
• piriform cortex
• prefrontal cortex
• pyriform cortex
• visual cortex

Rhymes for cortex

• vortex
• neocortex

Kids Definition

cortex

noun

cor·​tex ˈkȯr-ˌteks 

plural cortices ˈkȯrt-ə-ˌsēz  or cortexes

1

: an outer or surrounding layer of an organ or body part

the cortex of the kidney

especially : the outer layer of gray matter of the cerebrum

2

: the layer of tissue outside the xylem and phloem and inside the corky or epidermal tissues of a vascular plant

also : all tissues external to the xylem

Medical Definition

cortex

noun

cor·​tex ˈkȯr-ˌteks 

plural cortices ˈkȯrt-ə-ˌsēz  also cortexes

1

a

: the outer or superficial part of an organ or body structure (as the kidney, adrenal gland, or a hair)

especially : cerebral cortex

b

: the outer part of some organisms (as paramecia)

2

a

: a plant bark or rind (as cinchona) used medicinally

b

: the peel of any of several fruits

—used especially in the writing of medical prescriptions