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prefrontal cortex
noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
Examples of prefrontal cortex in a Sentence
Recent Examples on the Web
After birth, particles can also penetrate the prefrontal cortex—the part of the brain behind the forehead—after being inhaled through the nose.
—Debra Hendrickson, WIRED, 4 Jan. 2025
The ventromedial prefrontal cortex is involved with action control, memory, and making decisions.
—Elizabeth Rayne, Ars Technica, 30 Dec. 2024
This research suggests that introverts possess a thicker prefrontal cortex compared to extroverts, indicating more brain tissue in the region responsible for deep thinking and decision-making.
—Vibhas Ratanjee, Forbes, 26 Dec. 2024
Studies have also indicated that young people are particularly susceptible to impulse control issues due to a developing prefrontal cortex.
—Brian Curcio, Forbes, 9 Dec. 2024
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Word History
First Known Use
1892, in the meaning defined above
Time Traveler
The first known use of prefrontal cortex was
in 1892
Dictionary Entries Near prefrontal cortex
Cite this Entry
“Prefrontal cortex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal%20cortex. Accessed 21 Jan. 2025.
Medical Definition
prefrontal cortex
noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
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