leukotriene
noun
leu·ko·tri·ene
ˌlü-kō-ˈtrī-ˌēn 
: any of a group of eicosanoids that participate in allergic responses (such as bronchial constriction)
Examples of leukotriene in a Sentence
Recent Examples on the Web
Drugs that block leukotriene production (like zileuton) or leukotriene receptors (like montelukast, also commonly used for asthma) are already approved for other uses, which could speed up testing for food allergy applications, the study suggests.
—
Hannah Millington, MSNBC Newsweek, 28 Aug. 2025
Quercetin blocks pro-inflammatory chemicals, such as leukotrienes and prostaglandins.31
Due to limited research, there is no recommended or usual dose.
—Carol Eustice, Verywell Health, 18 Aug. 2025
What Are the Safest Allergy Medications for Daily Use?
Nasal steroid sprays and prescription medications, such as leukotriene receptor antagonists like montelukast (Singulair), are the safest allergy medications for long-term use.
—Jillian Kubala, Health, 28 Apr. 2025
Other medications include what are known as leukotriene modifiers, which block the action of inflammatory chemicals the immune system produces in the presence of allergens.
—Jeffrey Kluger, TIME, 25 June 2024
Seasonal allergies are the body’s response to pollen from trees and grass; the immune system releases chemicals, like histamines, leukotrienes, and prostaglandins, which cause all those uncomfortable, familiar symptoms.
—Allie Volpe, Vox, 7 Dec. 2018
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Hannah Millington, MSNBC Newsweek, 28 Aug. 2025
Quercetin blocks pro-inflammatory chemicals, such as leukotrienes and prostaglandins.31
Due to limited research, there is no recommended or usual dose.
—Carol Eustice, Verywell Health, 18 Aug. 2025
What Are the Safest Allergy Medications for Daily Use?
Nasal steroid sprays and prescription medications, such as leukotriene receptor antagonists like montelukast (Singulair), are the safest allergy medications for long-term use.
—Jillian Kubala, Health, 28 Apr. 2025
Other medications include what are known as leukotriene modifiers, which block the action of inflammatory chemicals the immune system produces in the presence of allergens.
—Jeffrey Kluger, TIME, 25 June 2024
Seasonal allergies are the body’s response to pollen from trees and grass; the immune system releases chemicals, like histamines, leukotrienes, and prostaglandins, which cause all those uncomfortable, familiar symptoms.
—Allie Volpe, Vox, 7 Dec. 2018
Cite this Entry
“Leukotriene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leukotriene. Accessed 9 Sep. 2025.
Copy CitationMedical Definition
leukotriene
noun
leu·ko·tri·ene
ˌlü-kə-ˈtrī-ˌēn
: any of a group of eicosanoids that are generated in basophils, mast cells, macrophages, and human lung tissue by lipoxygenase-catalyzed oxygenation especially of arachidonic acid and that participate in allergic responses (as bronchoconstriction in asthma) see slow-reacting substance of anaphylaxis
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