buprenorphine

noun

bu·​pre·​nor·​phine ˌbyü-prə-ˈnȯr-ˌfēn 

-fən

: a semisynthetic narcotic analgesic that is administered in the form of its hydrochloride C₂₉H₄₁NO₄·HCl to control moderate to severe pain and treat opioid dependence

Note: Buprenorphine is administered by injection to control pain, is used in the form of a transdermal skin patch to control pain or treat opioid dependence, and is used in combination with naloxone in the form of a dissolvable tablet placed under the tongue or film placed inside the cheek to treat opioid dependence.

Examples of buprenorphine in a Sentence

Recent Examples on the Web

Advertisement Methadone prescriptions issued by the health department increased by more than 30% and buprenorphine prescriptions by nearly 50% in the last year, Colfax said. —Hannah Wiley, Los Angeles Times, 1 Jan. 2025

After having struggled for years, Scott was prescribed buprenorphine in 2011. —Hannah Rappleye, NBC News, 24 Dec. 2024

The state of New York — which spent the most on treatment — allocated about $22 million of that for programs that make the gold standard for care as easy as possible for patients: providing same-day prescriptions for buprenorphine, a medication that decreases cravings for opioids. —Aneri Pattani, NPR, 16 Dec. 2024

Two of the most effective medications for opioid use disorder are Suboxone (buprenorphine/naloxone) and methadone. —Patricia Weiser, Pharmd, Verywell Health, 25 Oct. 2024

Word History

First Known Use

1974, in the meaning defined above

Medical Definition

buprenorphine

noun

bu·​pre·​nor·​phine ˌbyü-prə-ˈnȯr-ˌfēn, -fən 

: a semisynthetic narcotic analgesic that is derived from thebaine and is administered in the form of its hydrochloride C₂₉H₄₁NO₄·HCl to control moderate to severe pain and treat opioid dependence

Note: Buprenorphine is administered by injection to control pain, is used in the form of a transdermal skin patch to control pain or treat opioid dependence, and is used in combination with naloxone in the form of a dissolvable tablet placed under the tongue or film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing buprenorphine include Bunavail, Buprenex, Butrans, Subutex, Suboxone, and Zubsolv.