interstitial
adjective
in·ter·sti·tial
ˌin-tər-ˈsti-shəl 
1
: occurring in or being an interval or intervening space or segment : of, relating to, or forming an interstice
an interstitial space
… the site has been running interstitial ads, which consist of a full page of advertising between editorial pages, for a little more than a year.—
Carl Sullivan
Carl Sullivan2
a
: situated within but not restricted to or characteristic of a particular organ or tissue
—used especially of fibrous tissue
b
: affecting the interstitial tissues of an organ or part
interstitial cystitis
3
: being or relating to a crystalline compound in which usually small atoms or ions of a nonmetal occupy holes between the larger metal atoms or ions in the crystal lattice
Examples of interstitial in a Sentence
Recent Examples on the Web
Medications, genetics, and autoimmune diseases like sarcoidosis or rheumatoid arthritis can all cause interstitial lung disease.
—Mark Gurarie, Health, 14 Feb. 2025
The performance was emceed by Samuel L. Jackson dressed as Uncle Sam, setting up the songs and providing interstitial commentary.
—Time Staff, TIME, 10 Feb. 2025
Nickel Boys also deviates from traditional filmic language through the interstitial placement of archival footage.
—Hilton Dresden, The Hollywood Reporter, 9 Feb. 2025
CGMs typically connect to a smartphone via Bluetooth and measure glucose levels in the interstitial fluid just under your skin.
—Larry Magid, The Mercury News, 24 Jan. 2025
See All Example Sentences for interstitial
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Mark Gurarie, Health, 14 Feb. 2025
The performance was emceed by Samuel L. Jackson dressed as Uncle Sam, setting up the songs and providing interstitial commentary.
—Time Staff, TIME, 10 Feb. 2025
Nickel Boys also deviates from traditional filmic language through the interstitial placement of archival footage.
—Hilton Dresden, The Hollywood Reporter, 9 Feb. 2025
CGMs typically connect to a smartphone via Bluetooth and measure glucose levels in the interstitial fluid just under your skin.
—Larry Magid, The Mercury News, 24 Jan. 2025
See All Example Sentences for interstitial
Cite this Entry
“Interstitial.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/interstitial. Accessed 1 Mar. 2025.
Copy CitationKids Definition
interstitial
adjective
in·ter·sti·tial
ˌint-ər-ˈstish-əl
: relating to or located in the interstices
Medical Definition
interstitial
adjective
in·ter·sti·tial
ˌint-ər-ˈstish-əl
1
: situated within but not restricted to or characteristic of a particular organ or tissue
—used especially of fibrous tissue
2
: affecting the interstitial tissues of an organ or part
interstitial hepatitis
3
: occurring in the part of a fallopian tube in the wall of the uterus
interstitial pregnancy
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