insulin-like growth factor

noun

in·​su·​lin-like growth factor ˈin(t)-s(ə-)lən-ˈlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity

Examples of insulin-like growth factor in a Sentence

Recent Examples on the Web
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This affordable serum contains synthetic versions of epidermal, transforming, and insulin-like growth factors (EGF, TGF, and IGF, respectively) made of peptides to help renew skin. Emily Orofino, Vogue, 6 May 2025 People who take a GLP-1 medication also tend to have elevated levels of insulin-like growth factor 1 (IGF-1), a growth hormone that helps control sebum production. Claire Bugos, Verywell Health, 10 Apr. 2025 These peptides, in turn, activate the insulin-like growth factor 1 (IGF-1) signaling pathway in NSCs and triggers their reactivation. New Atlas, 15 Aug. 2024 Researchers are unsure exactly why dairy causes acne, but some evidence suggests that milk raises insulin-like growth factor 1 (IGF-1) levels, which increases sebum (oil) production. Kathleen Felton, Health, 11 Sep. 2023 In 1956 Daughaday discovered the hormone now called insulin-like growth factor 1, or IGF-1. Gary Taubes, Discover Magazine, 26 Mar. 2013

Word History

First Known Use

1976, in the meaning defined above

Time Traveler
The first known use of insulin-like growth factor was in 1976

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Cite this Entry

“Insulin-like growth factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin-like%20growth%20factor. Accessed 5 Sep. 2025.

Medical Definition

insulin-like growth factor

noun
in·​su·​lin-like growth factor ˌin(t)-s(ə-)lən-ˌlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity
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