hydrocodone

noun

hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound that is derived from codeine and is administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough suppressant

Examples of hydrocodone in a Sentence

Recent Examples on the Web
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During the crash, a police affidavit said Woods carried two hydrocodone pills, opioid painkillers, in his left pocket. Claire Carter, The Washington Examiner, 1 Apr. 2026 The Martin County Sheriff’s Office identified the pills in Woods’ pocket as the opioid pain medication hydrocodone. Brian Niemietz, New York Daily News, 1 Apr. 2026 Duncan represented Woods in the 2017 DUI case in which prescription drugs, including hydrocodone, were found in his system. Cindy Von Quednow, CNN Money, 1 Apr. 2026 The affidavit also said that a search of Woods yielded two hydrocodone pills in his pant pocket. Ryan Gaydos, FOXNews.com, 1 Apr. 2026 See All Example Sentences for hydrocodone

Word History

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of hydrocodone was in 1964

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Cite this Entry

“Hydrocodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydrocodone. Accessed 3 Apr. 2026.

Medical Definition

hydrocodone

noun
hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound derived from codeine and administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough sedative

called also dihydrocodeinone

see hycodan, vicodin
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