: a histamine analog C10H16N6S that inhibits gastric acid secretion and is used especially in the treatment of duodenal ulcers

Examples of cimetidine in a Sentence

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The authors cite a study using 400 milligrams of cimetidine three times daily, which is much higher than the heartburn dose. Joe and Teresa Graedon, oregonlive, 29 May 2023 Researchers offering case reports of success with cimetidine against shingles have called for robust clinical trials. Joe and Teresa Graedon, oregonlive, 29 May 2023

Word History

Etymology

ci- (alteration of cyan-) + methyl + -idine

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of cimetidine was in 1975

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Cite this Entry

“Cimetidine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cimetidine. Accessed 9 Apr. 2025.

Medical Definition

cimetidine

noun
: an H2 antagonist C10H16N6S that like histamine contains the ring structure of imidazole and is used to inhibit gastric acid secretion in conditions in which such secretion produces duodenal or gastric ulcers or erosive lesions (as in serious cases of gastroesophageal reflux disease) see tagamet

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