cholera

noun

chol·​era ˈkä-lə-rə 

: any of several diseases of humans and domestic animals usually marked by severe gastrointestinal symptoms

especially : an acute diarrheal disease caused by an enterotoxin produced by a comma-shaped gram-negative bacillus (Vibrio cholerae synonym V. comma) when it is present in large numbers in the proximal (see proximal sense 2) part of the human small intestine

Examples of cholera in a Sentence

Recent Examples on the Web

These human caravans walked for hours in up to 104-degree heat in an attempt to reach medical treatment, because their local clinics had either closed completely or run out of ways to treat cholera. —Charlie Warzel, The Atlantic, 24 June 2025

Sudan isn't the only country dealing with cholera; outbreaks have become increasingly common across Africa. —Maryanne Murray Buechner, Forbes.com, 5 June 2025

Scientists were only starting to piece together that contaminated water, not flawed character, caused cholera; that smallpox probably originated in rodents; and that yellow fever was the vector work of the lowly mosquito, not the result of immigration or rotting vegetables. —Paige Williams, New Yorker, 2 June 2025

The main treatment for cholera, which causes profuse watery diarrhea and vomiting, is oral rehydration. —Beth Mole, ArsTechnica, 11 Apr. 2025

Word History

Etymology

Latin

First Known Use

1601, in the meaning defined above

Phrases Containing cholera

• Asiatic cholera
• cholera morbus
• hog cholera

Kids Definition

cholera

noun

chol·​era ˈkäl-ə-rə 

: any of several diseases usually marked by severe vomiting and diarrhea

Medical Definition

cholera

noun

chol·​era ˈkäl-ə-rə 

: any of several diseases of humans and domestic animals usually marked by severe gastrointestinal symptoms: as

a

: an acute diarrheal disease caused by an enterotoxin produced by various strains of a comma-shaped gram-negative bacterium of the genus Vibrio (V. cholerae synonym V. comma) when it is present in large numbers in the proximal part of the human small intestine see asiatic cholera

b

: fowl cholera

c

: hog cholera

choleraic

ˌkäl-ə-ˈrā-ik 

adjective