gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌga-strō-in-ˈte-stə-nᵊl 

-ˈtes(t)-nəl

: of, relating to, affecting, or including both stomach and intestine

Examples of gastrointestinal in a Sentence

Recent Examples on the Web

Demand for the drug class has soared despite hefty price tags and a handful of unpleasant side effects that are most commonly gastrointestinal, such as nausea and vomiting. —Annika Kim Constantino,ashley Capoot, CNBC, 11 June 2025

Risks and limitations Diabetes and obesity medications are widely known to cause gastrointestinal issues in some patients — primarily nausea, with some reporting vomiting, constipation and diarrhea. —Melissa Rudy, FOXNews.com, 10 June 2025

Additionally, for patients who are typically sensitive to new medications—especially those who experience gastrointestinal issues—an oral daily option could provide more control, says Dr. Rebecca Emch, vice president of pharmacy and medical operations at Eden. —Elizabeth Yuko, Flow Space, 9 June 2025

This may be especially relevant for individuals with sensitive digestive systems or gastrointestinal conditions. —Daryl Austin, USA Today, 8 June 2025

Word History

First Known Use

1831, in the meaning defined above

Phrases Containing gastrointestinal

• gastrointestinal tract

Rhymes for gastrointestinal

• intestinal

Kids Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl 

: of, relating to, or including both stomach and intestine

Medical Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl, -ˈtes(t)-nəl 

: of, relating to, or affecting both stomach and intestine

gastrointestinal distress