endorphin

noun

en·​dor·​phin en-ˈdȯr-fən How to pronounce endorphin (audio)
: any of a group of endogenous peptides (such as enkephalin) found especially in the brain that bind chiefly to opiate receptors and produce some pharmacological effects (such as pain relief) like those of opiates
specifically : beta-endorphin

Did you know?

The word endorphin was coined, back when the substances were discovered in the 1970s, by joining pieces of endogenous and morphine, morphine being a narcotic that closely resembles the endorphins and relieves pain in a similar way. Studies suggest that the pain-relieving practice called acupuncture works by releasing endorphins. Endorphins also seem to play an important role in pregnancy. Though much remains to be learned about the endorphins, the general public seems ready to give them credit for any all-natural high.

Examples of endorphin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Chewing gives dogs a rush of endorphins, and chomping down on dental chew treats can be especially good for stimulating dogs indoors during particularly bad winter weather. Claire Thornton, USA TODAY, 13 Dec. 2024 Cognitive health Laughter positively impacts cognitive function by reducing stress hormones like cortisol, which can impair memory and learning, while stimulating the release of endorphins that improve mood and motivation. Sandra Rose Salathe, Flow Space, 11 Dec. 2024 Dancing also promotes the release of endorphins, chemicals that help promote feel-good neurotransmitters (chemicals that allow nerves to communicate) and reduce unpleasant emotions.1 8. Heidi Moawad, Verywell Health, 7 Dec. 2024 We’d be horrified and trembling with trauma endorphins. Ed Herro, The Hollywood Reporter, 6 Dec. 2024 See all Example Sentences for endorphin 

Word History

Etymology

International Scientific Vocabulary endogenous + morphine

First Known Use

1976, in the meaning defined above

Time Traveler
The first known use of endorphin was in 1976

Dictionary Entries Near endorphin

Cite this Entry

“Endorphin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endorphin. Accessed 14 Jan. 2025.

Medical Definition

endorphin

noun
en·​dor·​phin en-ˈdȯr-fən How to pronounce endorphin (audio)
: any of a group of endogenous peptides (as enkephalin and dynorphin) found especially in the brain that bind chiefly to opiate receptors and produce some of the same pharmacological effects (as pain relief) as those of opiates
specifically : beta-endorphin

More from Merriam-Webster on endorphin

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!