How to Use polymerase in a Sentence

polymerase

noun

• The switch kicks in to stop the spiral from unzipping too far and lets the polymerase catch up.
  — NBC News, 20 June 2017
• As polymerase inhibitors, remdesivir and favipiravir are the same class of drug, Abbas said.
  — Naomi Xu Elegant, Fortune, 28 Mar. 2020
• One type is called a polymerase chain reaction, or P.C.R., designed to detect the active virus in blood and urine.
  — Roni Caryn Rabin, New York Times, 19 Sep. 2016
• The piece of machinery in question is an enzyme called polymerase.
  — Elizabeth Preston, Discover Magazine, 19 Jan. 2011
• The drug is a polymerase inhibitor that induces a destructive number of mutations to the virus.
  — William A. Haseltine, Forbes, 4 Jan. 2022
• The simplest, known as a polymerase chain reaction test, can find traces of the virus in the blood up until about a week after infection, and in urine for about 10 days.
  — Marc Santora, New York Times, 17 June 2016
• In 2016, Zhu and his colleagues took a first stab at the task, synthesizing a mirror-image version of a polymerase from a virus.
  — Byrobert F. Service, science.org, 27 Oct. 2022
• And that will be carried out by a whole set of molecular machines, the polymerase and things like that, that are basically just doing that all the time in the cell.
  — Steven Strogatz, Quanta Magazine, 8 Mar. 2023
• It has been shown to work against RNA-polymerase, the enzyme that is responsible for the virus multiplying.
  — Manavi Kapur, Quartz, 1 Oct. 2021
• That window is rather narrow for all polymerase and protease inhibitors.
  — William A. Haseltine, Scientific American, 1 Oct. 2020
• That’s prompted dreams of reengineering polymerases to write new DNA.
  — Robert F. Service, Science | AAAS, 18 June 2018
• Molnupiravir is what’s known as a polymerase inhibitor.
  — Colleen Stinchcombe, SELF, 30 Nov. 2021
• Those changes, particularly in the polymerase gene, are not present in most current day H5N1 viruses.
  — Helen Branswell, STAT, 4 May 2022
• Once inside cells, the virus uses an enzyme called a polymerase to grab those building blocks and assemble them into new copies of viral RNA.
  — Stephani Sutherland, Scientific American, 1 Dec. 2021
• The viral polymerase acid amplification test is performed with a nasal swab.
  — Steve Sadin, chicagotribune.com, 16 Oct. 2020
• The researchers used its genes to resurrect the virus’ polymerase complex, a machinery consisting of three proteins that together copy the pathogen’s genome.
  — Kai Kupferschmidt, Science | AAAS, 17 May 2021
• Sequenced virus samples from four mink show several changes compared with the bird virus, including T271A, a mutation in the gene for an enzyme, polymerase.
  — Bykai Kupferschmidt, science.org, 24 Jan. 2023
• But the chicken decoy mimics influenza's latching-on spot, so the polymerase attaches to the decoy and sits there uselessly.
  — Elizabeth Preston, Discover Magazine, 19 Jan. 2011
• This protein is the polymerase, which controls viral replication.
  — William A. Haseltine, Forbes, 17 Mar. 2021
• That said, this drug was designed with the intention of inhibiting the polymerase of a different virus (Ebola), so it wasn't guaranteed to work against coronavirus.
  — John Timmer, Ars Technica, 1 May 2020
• Until now, scientists believed that the polymerases on the two strands coordinated their movement somehow to ensure that one didn’t get too far ahead of the other.
  — NBC News, 20 June 2017
• The molecule that made the new RNAs most efficiently, known as polymerase ribozyme 24-3, worked surprisingly well.
  — Quanta Magazine, 25 Aug. 2016
• Xofluza interferes with a protein inside the flu virus called polymerase acidic endonuclease, which helps stop the virus from replicating, Dr. Adalja explains.
  — Korin Miller, SELF, 26 Oct. 2018
• Another one of Wang’s projects, which is still at an early stage, also focuses on viral polymerase but has a different target to baloxavir.
  — Neil Savage, Scientific American, 18 Sep. 2019
• Before rush orders of the HCV drug and polymerase inhibitor combo can be placed, the therapy must be tested in animal models and clinical studies.
  — William A. Haseltine, Forbes, 5 May 2021
• Once it is recopied, the replicating polymerase develops transition mutations, where a U nucleotide is converted to a C and a C to U.
  — William A. Haseltine, Forbes, 8 Oct. 2021
• Studies in mashed-up and preserved cells had hinted that many polymerase molecules cluster together to make this mRNA magic happen.
  — Alla Katsnelson and Casey Rentz, Discover Magazine, 3 May 2019
• The case went cold, but in 2001, authorities were able to review old evidence using a technology called PCR, or polymerase chain reaction.
  — Channon Hodge, CNN, 9 June 2017
• So Ho is stacking his shelves with polymerase and protease inhibitors and other drugs that have been developed to fight HIV and other viruses like viral hepatitis, that can interfere with this replication.
  — Alice Park, Time, 26 Feb. 2020
• To try to slow it, many countries are starting to deploy tests which, at some cost in accuracy, deliver their results much more rapidly than the polymerase-chain-reaction (PCR) tests that were commonplace at the pandemic’s beginning.
  — The Economist, 14 Nov. 2020

Last Updated: 17 Jul 2024