How to Use oligonucleotide in a Sentence

oligonucleotide

noun

• To that end, the researchers turned to something called antisense oligonucleotides.
  — Lydia Denworth, Scientific American, 3 Mar. 2020
• The newest oligonucleotide drugs are designed to tackle rare diseases.
  — Lydia Denworth, Scientific American, 3 Mar. 2020
• The company's encoding starts with a library of dozens to hundreds of short pieces of DNA called oligos (short for oligonucleotide).
  — John Timmer, Ars Technica, 15 Sep. 2022
• But any chain that is short—usually 15 to 20 nucleotides—is considered an oligonucleotide.
  — Lydia Denworth, Scientific American, 3 Mar. 2020
• But one patient advocacy group has publicly shared that Yu’s team has designed an oligonucleotide for a toddler with ataxia-telangiectasia, a neurodegenerative disorder, and hoped to begin to treat her this fall.
  — Jocelyn Kaiser, Science | AAAS, 9 Oct. 2019
• An alternative treatment, drugs based on chemicals known as antisense oligonucleotides, is in clinical trials.
  — Nicholas Wade, New York Times, 31 Dec. 2015
• Upon receipt, the sequence is run through biosafety and biosecurity checks, and ultimately constructed through the enzymatic assembly of shorter oligonucleotide chains.
  — Jeffrey Marlow, WIRED, 31 Mar. 2015
• The drug is a synthetic genetic molecule — known as an oligonucleotide — similar to Biogen’s therapy for spinal muscular atrophy, Spinraza.
  — Ryan Cross, BostonGlobe.com, 8 Dec. 2022
• Krainer is co-founder of Stoke Therapeutics, a company focused on treating severe genetic disease using antisense oligonucleotides.
  — Bret Stetka, Scientific American, 15 Aug. 2019

Last Updated: 24 Jul 2024