How to Use nucleotide in a Sentence

nucleotide

noun
  • Recall the four nucleotide bases that make up the DNA ladder.
    Courtney Linder, Popular Mechanics, 25 July 2020
  • The nucleotides themselves each contained one of four bases.
    Kat Eschner, Smithsonian, 7 Mar. 2017
  • The nucleotides themselves each contained one of four bases.
    Kat Eschner, Smithsonian, 7 Mar. 2017
  • And there’s the toxin itself, which edits the nucleotide.
    Nathaniel Scharping, Discover Magazine, 9 Dec. 2020
  • The mutation closest to the 5’ end of the genome is the C241U nucleotide substitution.
    William A. Haseltine, Forbes, 3 Sep. 2021
  • So the researchers decided to hack that hunger for nucleotides.
    Megan Molteni, WIRED, 26 Apr. 2018
  • Of the three billion nucleotide pairs that make up my chromosomes, there was one mistake.
    Sarah Stewart Johnson, The New Yorker, 4 Oct. 2020
  • Until the microarray, scientists trying to make sense of the letters would have had to pick through that heap a few nucleotides a time.
    Brian Alexander, WIRED, 1 June 2000
  • If the food has one of the two nucleotides – inosinate and guanylate – the glutamate is able to stick to the receptor for a longer period.
    Maggie Hiufu Wong, CNN, 9 May 2023
  • The enzymes used in the new technique sever the bond linking one nucleotide to another to create a nick in the sugar-phosphate rails.
    Charles Q. Choi, Scientific American, 8 Apr. 2020
  • By comparison, a single nucleotide of DNA—one of the basic letters that make up our genes—would fit in a cube about a nanometer wide.
    Scott Penberthy, Scientific American, 7 Dec. 2022
  • Look to your 46 chromosomes and three billion nucleotide base pairs.
    Oliver Whang, New York Times, 12 Sep. 2022
  • In an insertion or deletion, though, the DNA gets an extra nucleotide base, or removes one.
    Courtney Linder, Popular Mechanics, 25 July 2020
  • With sufficient funding, the writing of genomes on the billion-nucleotide scale could be a reality before the end of this decade.
    Andrew Hessel, Scientific American, 10 Nov. 2020
  • Of her billions of nucleotides, which are the single bricks that make up her genes, the authors identified 3 million variations.
    Ben Guarino, BostonGlobe.com, 23 Mar. 2018
  • But the virus with the S139N mutation — in which only one nucleotide differs from the Cambodian version — killed more mice and caused more brain damage.
    Pam Belluck and Donald G. McNeil Jr., New York Times, 28 Sep. 2017
  • Writ in those nucleotides is a record of your most intimate kin and medical history.
    Robert Hackett, Fortune, 28 Apr. 2018
  • The drink contains arginine, an amino acid; certain nucleotides; and fish oil, which helps fight inflammation.
    Shari Rudavsky, USA TODAY, 2 May 2017
  • Viruses steal a cell’s nucleotides to make more copies of itself, using a special enzyme as their engine of self-replication.
    Megan Molteni, WIRED, 8 July 2019
  • When that enzyme grabs favipiravir instead of a nucleotide, the virus’s multiplication machinery gets gummed up and grinds to a halt.
    Megan Molteni, WIRED, 8 July 2019
  • For genomes, that means synthesizing DNA one nucleotide at a time and stringing together thousands of them.
    Sharon Begley, STAT, 1 May 2018
  • There is a lot of repetition, beginning with the two strands of nucleotides that zip together to form DNA’s double helix.
    Lydia Denworth, Scientific American, 3 Mar. 2020
  • In a frameshift an added or deleted molecular building block called a nucleotide throws a wrench into a cell’s replication gearbox.
    Keridwen Cornelius, Scientific American, 7 June 2018
  • This protein is the engine of the transcription-replication complex, reading nucleotide sequences and copying them for the creation of new RNA.
    William A. Haseltine, Forbes, 22 Oct. 2021
  • The tags are engineered to embed up to 250 bits of identifying information in the sequence of DNA nucleotides.
    Matt Allyn, Popular Mechanics, 15 May 2018
  • Genesis is about choosing what to invest in, reflecting the long odds of nucleotides bonding together to form RNA.
    Dan Thurot, Ars Technica, 25 Apr. 2020
  • These diseases are caused by an unusual genetic change — an expansion of a segment of DNA that contains a repeat of three nucleotides.
    Jonathan Saltzman, BostonGlobe.com, 17 Dec. 2019
  • An international team of researchers mapped the genome of quinoa, determining that the grain has 1.3 billion nucleotides (the building blocks of DNA) spread over 18 chromosomes.
    Jason Daley, Smithsonian, 13 Feb. 2017
  • While Crispr is often described as scissors that snips segments of DNA, base editing is even more precise, allowing for single nucleotide changes.
    Leah Rosenbaum, Forbes, 2 June 2021
  • Once it is recopied, the replicating polymerase develops transition mutations, where a U nucleotide is converted to a C and a C to U.
    William A. Haseltine, Forbes, 8 Oct. 2021

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'nucleotide.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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