How to Use kinase in a Sentence

kinase

noun

• That signal involves the production of a type of cytokine called a Janus kinase, or JAK.
  — Marla Broadfoot, Scientific American, 1 Sep. 2021
• Tanzi and his colleagues blocked a variety of different enzymes called kinases to try to stop the process.
  — Karen Weintraub, Scientific American, 16 Jan. 2020
• The drug belongs to a large class of cancer drugs called tyrosine kinase inhibitors, the fruits of research by Tony Hunter at the Salk Institute four decades ago.
  — San Diego Union-Tribune, 17 Sep. 2019
• The virus most powerfully hijacks a kinase called CK2, which plays a key role in the basic frame of the cell as well as its growth, proliferation and death.
  — Mark Johnson, Milwaukee Journal Sentinel, 27 June 2020
• The tests also look for whether the blood increases CaM kinase II activity.
  — Pamela Weintraub, Discover Magazine, 3 Jan. 2019
• Among them was a compound called silmitasertib, which inhibits a kinase called CK2, and is being tested as a cancer drug.
  — Gregory Barber, Wired, 27 June 2020
• The tests were performed by virologists at Mount Sinai and the Institut Pasteur, who infected host cells with the virus and added the kinase inhibitors.
  — Jason Fagone, SFChronicle.com, 26 June 2020
• In more severe cases, some patients may use Janus kinase inhibitors.
  — NBC News, 7 Jan. 2022
• Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna.
  — WIRED, 4 Sep. 2023
• Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid.
  — Christine Coppa, Health, 15 Mar. 2023
• You may then be given tyrosine kinase inhibitors (TKIs), targeted therapy drugs that send signals to the cells to stop that growth.
  — Gagandeep Brar, Verywell Health, 19 Mar. 2023
• Zelboraf targets patients who test positive for a variant of the BRAF gene, another kinase that can go haywire and cause cells to grow out of control.
  — David Ewing Duncan, Discover Magazine, 30 Oct. 2012
• But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250.
  — David Ewing Duncan, Discover Magazine, 30 Oct. 2012
• One street that seemed particularly active was ruled by a kinase called Casein Kinase II, which happened to be one of the 332 proteins flagged in the team’s earlier protein map.
  — Jason Fagone, SFChronicle.com, 26 June 2020
• ArQule, based in Woburn, Mass., is focused on kinase inhibitor discovery.
  — Washington Post, 9 Dec. 2019
• The startup is developing drugs that rely on enzyme blockers known as kinase inhibitors to keep cancer cells from growing.
  — BostonGlobe.com, 29 July 2021
• Finally, Krogan and his colleagues found that the virus also hijack a kinase that helps cells stay healthy in different environments and cleans out damaged cells.
  — Mark Johnson, Milwaukee Journal Sentinel, 27 June 2020
• The startup is developing lung cancer drugs that rely on enzyme blockers known as kinase inhibitors to help keep cancer cells from growing.
  — BostonGlobe.com, 14 May 2021
• One drug candidate emerged at the top of the pack: c-Jun N-terminal kinase inhibitor SU3327, which is already being studied as a possible treatment for diabetes.
  — Quanta Magazine, 9 Mar. 2020
• Spectrum of discovery The Nature study can be viewed as an extension of Hunter’s groundbreaking work in tyrosine kinases.
  — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
• Drugs called kinase inhibitors work by changing cellular function to fight itchiness.
  — Dr. Marty Becker and Kim Campbell Thornton, sacbee.com, 28 Apr. 2017
• Pyrukynd is a pill for a hereditary blood disorder called pyruvate kinase deficiency.
  — Globe Staff, BostonGlobe.com, 12 July 2022
• For his part, Hunter performed research that led to an entirely new category of cancer drugs called tyrosine kinase inhibitors.
  — San Diego Union-Tribune, 19 Aug. 2019
• Hunter made his reputation with the 1979 discovery of how enzymes called tyrosine kinases can cause cancer.
  — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
• Given as a pill, mitapivat is designed to activate an enzyme called pyruvate kinase-R that red blood cells use to convert sugars into energy.
  — Adam Feuerstein, STAT, 18 Feb. 2022
• Such tyrosine kinase inhibitors constitute a large class of cancer drugs, made possible by the research of Salk Institute scientist Tony Hunter.
  — Bradley J. Fikes, sandiegouniontribune.com, 4 Sep. 2017
• Most recently, autoimmune drugs known as Janus kinase inhibitors -- JAK inhibitors -- have been found to produce a full head of hair in patients with moderate to severe alopecia areata, a type of baldness that affects both men and women.
  — Susan Scutti, CNN, 9 May 2018
• In 1998 Druker started a clinical trial with his tyrosine kinase inhibitor.
  — Tony Dajer, Discover Magazine, 7 Feb. 2010
• These proteins, called receptor-like kinases, or RLKs, contain a sensory area outside the cell membrane that attaches to molecules in the environment.
  — Lakshmi Sandhana, WIRED, 5 Apr. 2003
• Choanoflagellates have genes for tyrosine kinases, enzymes that, in complex animals, help control the functions of specialized cells, such as insulin secretion in the pancreas.
  — Elizabeth Pennisi, Science | AAAS, 28 June 2018

Last Updated: 28 Sep 2024