How to Use epigenome in a Sentence

epigenome

noun
  • To do this, Sinclair’s team developed ICE, short for inducible changes to the epigenome.
    Sandee Lamotte, CNN, 12 Jan. 2023
  • Since all cells have the same DNA blueprint, the epigenome is what makes skin cells turn into skin cells and brain cells into brain cells.
    Alice Park, Time, 12 Jan. 2023
  • David had long suspected that the epigenome was central to longevity.
    Margaret Talbot, The New Yorker, 11 Aug. 2021
  • Likewise, alterations to the epigenome, which controls which genes are turned on and off, can cause cells to read the wrong genes and lose their function over time.
    Lori Miller Kase, Discover Magazine, 9 Apr. 2022
  • The researchers who have developed base editing even dream of reaching into the epigenome.
    The Economist, 26 Oct. 2017
  • Penick said the Indian jumping ant colonies used in the study were the same ones that were collected in India almost 20 years ago and were the first epigenome for the species sequenced.
    NBC News, 14 Apr. 2021
  • The epigenome itself is controlled by agents that add or subtract chemical groups, known as marks, to its proteins.
    Tad Friend, The New Yorker, 24 Mar. 2017
  • Adverse events while one is in utero may affect one’s epigenome, a set of chemical compounds that tell the genome what to do and regulates aging.
    Byerin Prater, Fortune, 10 Nov. 2022
  • Could the team activate telomerase to rejuvenate the epigenome?
    Margaret Talbot, The New Yorker, 11 Aug. 2021
  • That is, in the epigenome, a landscape of proteins and chemicals that sits atop your genetic material.
    Sonya Collins, Fortune Well, 23 Feb. 2023
  • Neretti focuses on the epigenome, looking for changes in DNA organization in the nucleus and which genes are turned on or off in senescent and normal cells.
    Monique Brouillette, Popular Mechanics, 21 Feb. 2023
  • The epigenome, a kind of cellular operating system, regulates which genes are turned on, or expressed, and which turned off, or not expressed.
    Robert Weisman, BostonGlobe.com, 12 Jan. 2023
  • Cells treated with Yamanaka factors, erases marks on the epigenome, losing their identity thus the reversal to the embryonic state (stem cell).
    Stephen Ibaraki, Forbes, 13 May 2022
  • One intriguing finding in the twin study was that changes the researchers noted in Kelly’s genome and epigenome (markers on our genes that develop in response to environmental stressors) occurred in the last six months of the mission.
    Brian Resnick, Vox, 18 July 2019
  • Environmental factors such as diet, stress, and sun exposure can affect the epigenome.
    Marcia Desanctis, Vogue, 21 July 2018
  • David published a great paper in Nature late last year showing that in mice Yamanaka gene therapy can safety reprogram the epigenome of the retina and restore vision in a mouse model of glaucoma.
    Alex Zhavoronkov, Forbes, 14 June 2021
  • The Stanford approach utilizes powerful agents known as Yamanaka factors, which reprogram a cell’s epigenome to its time zero, or embryonic state.
    Nicholas Wade, New York Times, 24 Mar. 2020
  • Proposing a more nuanced narrative than conventional wisdom about the immutability of our DNA, the epigenome has been identified as the control panel for our genes, determining which of them is turned on or off at any given time.
    Marcia Desanctis, Vogue, 21 July 2018
  • Our environment can rework our epigenome, and some studies suggest that this reworking may produce long-term changes in personality.
    Carl Zimmer, Discover Magazine, 17 June 2010
  • Skinner's own research in animals suggests changes to the epigenome, a swirl of biological factors that affect how genes are expressed, can be passed down through multiple generations.
    Andrew Curry, Science | AAAS, 18 July 2019
  • Meticulous tinkering with the epigenome, otherwise known as the control panel for our genes, has yielded a number of significant findings of late—but perhaps none so surreal as those reported in a recent report by Newsweek.
    Lauren Valenti, Vogue, 23 July 2018
  • During fetal development, chemical triggers called epigenomes cause cells to differentiate, so that some become muscle and others become bone, nerves, skin, or tissue.
    Anya Groner, Longreads, 9 June 2017
  • The epigenome literally turns genes on and off, often based on environmental triggers and human behaviors such as smoking, eating an inflammatory diet or suffering a chronic lack of sleep.
    Sandee Lamotte, CNN, 27 Sep. 2022

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'epigenome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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