Words to Describe modifications

How modifications often is described ("________ modifications")

• such
• subtle
• molecular
• essential
• allotropic
• necessary
• simple
• certain
• substantial
• obvious
• various
• reasonable
• many
• several
• gradual
• posttranslational
• only
• environmental
• additional
• important
• innumerable
• suitable
• few
• minor
• appropriate
• later
• covalent
• chemical
• genetic
• corresponding
• suggested
• peculiar
• minimal
• translational
• further
• induced
• considerable
• frequent
• adaptive
• occasional
• functional
• slight
• behavioral
• mental
• recent
• statutory
• following
• possible
• numerous
• structural
• successive
• morphological
• profound
• dietary
• drastic
• significant
• subsequent
• major
• extensive
• crystalline
• dependent
• radical
• technical