prefrontal cortex

noun

: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning

Examples of prefrontal cortex in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The prefrontal cortex, responsible for decision-making and focus, starts to lag. Dr. Diane Hamilton, Forbes.com, 31 Mar. 2025 Neuroimaging studies reveal that labeling emotions through writing activates the prefrontal cortex while dampening amygdala activity, effectively reducing emotional reactivity. Drew Ramsey, Contributor, CNBC, 25 Mar. 2025 Neuroscience research has shown that stress impairs the prefrontal cortex, the part of the brain responsible for logical decision-making. Margie Warrell, Forbes, 12 Mar. 2025 Curiosity, by asking questions, pulls us out of the emotional part of the brain and back into the logical reasoning part, the prefrontal cortex. Melinda Fouts, Ph.d., Forbes, 21 Mar. 2025 See All Example Sentences for prefrontal cortex

Word History

First Known Use

1892, in the meaning defined above

Time Traveler
The first known use of prefrontal cortex was in 1892

Browse Nearby Words

Cite this Entry

“Prefrontal cortex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal%20cortex. Accessed 14 Apr. 2025.

Medical Definition

prefrontal cortex

noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!