melancholia
noun
mel·an·cho·lia
ˌme-lən-ˈkō-lē-ə
1
: severe depression characterized especially by profound sadness and despair
Tense, irritable, I crashed into a fit of melancholia and found myself crying over inconsequential problems.—Susan Wood
A depressed Johnson was not the father figure that Boswell, himself prey to … bouts of melancholia and insecurity, wanted to celebrate.—Brooke Allen
2
: a sad quality or mood : melancholy
There's a touching melancholia to his voice …—Ralph Novak
Like Wallace's breakthrough novel, "Infinite Jest," "The Pale King" is pervaded by an air of melancholia, an acute sense of loss.—Tom McCarthy
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Merriam-Webster unabridged
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