hydroxyproline

noun

hy·​droxy·​pro·​line hī-ˌdräk-sē-ˈprō-ˌlēn How to pronounce hydroxyproline (audio)
: an amino acid C5H9NO3 that occurs naturally as a constituent of collagen

Examples of hydroxyproline in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The gel mask does so with three types of collagen, working in tandem with a thoughtful blend of supportive ingredients like hydroxyproline, collagen amino acids, hyaluronic acid, peptides, and squalane for a well-rounded formula that not only firms, but hydrates, soothes, and plumps. Kiana Murden, Vogue, 21 Mar. 2025 In the new study, researchers aimed to turn things around by targeting hydroxyproline — an amino acid present in mammalian collagen — that was drawn from a sample of the Lapedo child’s right radius. Jack Knudson, Discover Magazine, 10 Mar. 2025 To determine the child’s age, scientists extracted a specific amino acid called hydroxyproline from collagen in the bones. Sarah Kuta, Smithsonian Magazine, 10 Mar. 2025 Glycine helps to stabilize the collagen molecule, proline promotes collagen formation, and hydroxyproline is necessary for the correct structure of collagen fibers. Amber Smith, Discover Magazine, 23 Mar. 2022 The collagen molecule is made up of three amino acids: glycine, proline, and hydroxyproline. Amber Smith, Discover Magazine, 23 Mar. 2022 The star ingredient - soy proteins - are rich in the amino acid hydroxyproline, which is known to improve elasticity and smooth skin to promote a healthy-looking complexion. Grooming Playbook, The Salt Lake Tribune, 13 May 2022 The salon and nail-care brand Tenoverten created a restorative hand cream with a formula that, thanks to its proprietary blend of five oils, not only locks in moisture but also builds collagen and brightens skin using hydroxyproline and Kakadu plum. Caitie Kelly, New York Times, 19 Mar. 2020 The supplements specifically contain high amounts of three amino acids that are key building blocks for collagen synthesis in the body: glycine, proline and hydroxyproline. Lisa Drayer, CNN, 17 Oct. 2019

Word History

First Known Use

1905, in the meaning defined above

Time Traveler
The first known use of hydroxyproline was in 1905

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Cite this Entry

“Hydroxyproline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydroxyproline. Accessed 26 Mar. 2025.

Medical Definition

hydroxyproline

noun
hy·​droxy·​pro·​line -ˈprō-ˌlēn How to pronounce hydroxyproline (audio)
: an amino acid C5H9NO3 that occurs naturally as a constituent of collagen

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