haplotype

noun

hap·​lo·​type ˈha-plō-ˌtīp 

: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit

Examples of haplotype in a Sentence

Recent Examples on the Web

Specific combinations of these mutations—called a haplotype—seem to confer a higher risk of developing type 1 diabetes. —Amanda Gardner, Health, 20 Nov. 2023

In the absence of allelic competitors this variant sweeps up in frequency extremely rapidly, and flanking regions of the genome generate a long haplotype block. —Razib Khan, Discover Magazine, 13 Sep. 2013

On the other hand, the haplotype which is present in both the Basque and Punjabis is likely to be descended from a common set of individuals, implying that there is a genealogical chain connecting these two very distinct and distant Eurasian populations. —Razib Khan, Discover Magazine, 16 Jan. 2012

And Genghis Khan left his personal imprint on the populations of today, in the form of a set of genes, called a haplotype, common to about 0.5 percent of men today. —Nathaniel Scharping, Discover Magazine, 17 Oct. 2020

Word History

First Known Use

1967, in the meaning defined above

Medical Definition

haplotype

noun

hap·​lo·​type -ˌtīp 

: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit