dysregulation

noun

dys·​reg·​u·​la·​tion ˌdis-ˌreg-yə-ˈlā-shən, -ˌreg-ə- 

: impairment of a physiological regulatory mechanism (as that governing metabolism, immune response, or organ function)

dysregulated

-ˈreg-yə-ˌlāt-əd, -ˈreg-ə- 

adjective