: the coiled structural arrangement of many proteins consisting of a single chain of amino acids stabilized by hydrogen bonds
alpha-helical adjective

Word History

First Known Use

1951, in the meaning defined above

Time Traveler
The first known use of alpha-helix was in 1951

Browse Nearby Words

Cite this Entry

“Alpha-helix.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/alpha-helix. Accessed 20 Apr. 2025.

Medical Definition

alpha-helix

noun
al·​pha-he·​lix
: the coiled structural arrangement of many proteins consisting of a single chain of amino acids stabilized by hydrogen bonds compare beta-sheet, double helix

More from Merriam-Webster on alpha-helix

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!