Hand-Schüller-Christian disease

noun

Hand-Schül·​ler-Chris·​tian disease ˌhand-ˌshü-lər-ˈkris(h)-chən- 

: an inflammatory histiocytosis associated with disturbances in cholesterol metabolism that occurs chiefly in young children and is marked by cystic defects of the skull and by exophthalmos and diabetes insipidus

called also Schüller-Christian disease