Lesch-Nyhan syndrome

noun

Lesch-Ny·​han syndrome ˈlesh-ˈnī-ən- 

: a rare and usually fatal genetic disorder of male children that is inherited as an X-linked recessive trait and is characterized by hyperuricemia, intellectual disability, spasticity, compulsive biting of the lips and fingers, and a deficiency of hypoxanthine-guanine phosphoribosyltransferase

called also Lesch-Nyhan disease