Hirschsprung's disease

noun

Hirsch·​sprung's disease ˈhirsh-ˌpru̇ŋz- 

: megacolon that is caused by congenital absence of ganglion cells in the muscular wall of the distal part of the colon with resulting loss of peristaltic function in this part and dilatation of the colon proximal to the aganglionic part

called also congenital megacolon