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Testing for Lyme can be complicated but the CDC recommends using a combination of antibody tests, including an immunoassay antibody test like ELISA followed by an immunoblot antibody test like the western blot test.—Linda Carroll, NBC News, 18 Nov. 2023 The western blot test is actually less sensitive to antibodies than the ELISA test is (which is why doctors don’t just start with it), but once the ELISA test detects the antibodies, the western blot does a better job of confirming their source.—Jeffrey Kluger, Time, 16 June 2023
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