1
: a female fox
2
: a shrewish, ill-tempered woman
When Arabella called her a treacherous vixen and a heartless, profligate hussy, she spoke out freely, and said that she wasn't going to be abused.—Anthony Trollope
3
informal
: a sexually attractive woman
In this spy spoof, our hero, aided by a sexy vixen, … saves the world from a power-mad despot …—Steven Rebello
Love words? Need even more definitions?
Merriam-Webster unabridged
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