ulcer

noun

ul·​cer ˈəl-sər How to pronounce ulcer (audio)
1
: a break in skin or mucous membrane with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus
2
: something that festers and corrupts like an open sore
ulcer verb

Examples of ulcer in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Importantly, there was no increased risk of side effects such as conjunctivitis, oral ulcers and herpes infections, which are often seen with other eczema medications, so that is a positive differentiator for Rezpeg. New Atlas, 24 June 2025 Cytotec, a brand name for misoprostol, was registered as an ulcer medication and sold in Mexican pharmacies without a prescription; anyone could walk in and buy it. Rebecca Grant june 24, Literary Hub, 24 June 2025 Misoprostol, which causes contractions that empty the uterus, has multiple medical uses, including treating ulcers. Liana Simstrom, NPR, 22 June 2025 Cancer, intestinal infections, and stomach ulcers can also cause sticky poop. Sherri Gordon, Health, 21 June 2025 See All Example Sentences for ulcer

Word History

Etymology

Middle English, from Latin ulcer-, ulcus; akin to Greek helkos wound

First Known Use

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of ulcer was in the 14th century

Browse Nearby Words

Cite this Entry

“Ulcer.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ulcer. Accessed 4 Jul. 2025.

Kids Definition

ulcer

noun
ul·​cer ˈəl-sər How to pronounce ulcer (audio)
: a slow-healing open sore in which tissue breaks down

Medical Definition

ulcer

1 of 2 noun
ul·​cer ˈəl-sər How to pronounce ulcer (audio)
: a break in skin or mucous membrane with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus
a stomach ulcer

ulcer

2 of 2 verb
ulcered; ulcering ˈəls-(ə-)riŋ How to pronounce ulcer (audio)

More from Merriam-Webster on ulcer

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