truth serum

noun

: a hypnotic or anesthetic held to induce a subject under questioning to talk freely

Examples of truth serum in a Sentence

Recent Examples on the Web

The playfulness kicks in when George and Kathryn invite the other suspects over for a dinner spiced with garlic and truth serum. —Amy Nicholson, Los Angeles Times, 13 Mar. 2025

He’s dosed that particular dish with truth serum, the better to get tongues flapping around the dinner table. —Stephanie Zacharek, TIME, 6 Mar. 2025

With Her Half-Up Space Buns Hilary Duff Expressed Her Cat-Lady Pride With a $28 Hair Clip Now, watch Drag Race stars sip some truth serum: Follow Allure on Instagram and TikTok, or subscribe to our newsletter to stay up to date on all things beauty. —Marci Robin, Allure, 18 Feb. 2025

Moment of truth for DeAndre Hopkins Former Pro Bowl wideout Brandon Marshall apparently dumped truth serum into DeAndre Hopkins’ water bottle. —Nate Taylor, The Athletic, 4 Feb. 2025

Word History

First Known Use

1913, in the meaning defined above

Rhymes for truth serum

• variorum
• antiserum
• theorem
• thiram

Medical Definition

truth serum

noun

: a hypnotic or anesthetic (as thiopental) held to induce a subject under questioning to talk freely