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For example, most viruses lack aminoacyl tRNA synthetase enzymes, which shuttle amino acids onto transfer RNA molecules; these in turn make their way to the ribosome, dropping off their cargo to build proteins from the chains of amino acids.—Jeffrey Marlow, Discover Magazine, 20 Apr. 2017 So, the researcher team inserted strands of tRNA into the E. coli that would tell the codons brought in by the viruses to produce the wrong amino acids.—Jackie Appel, Popular Mechanics, 5 May 2023 To find out, the team compared Klosneuvirus’s aminoacyl tRNA synthetase sequences with other forms of the enzymes across the tree of life.—Jeffrey Marlow, Discover Magazine, 20 Apr. 2017 Lovisa Afzelius, an origination partner at Flagship Pioneering and chief executive of Alltrna, says the company could potentially use a single tRNA drug to treat thousands of diseases that stem from the same genetic mutation.—BostonGlobe.com, 9 Nov. 2021
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