tolerance

noun

tol·​er·​ance ˈtä-lə-rən(t)s 

ˈtäl-rən(t)s

1

: capacity to endure pain or hardship : endurance, fortitude, stamina

2

a

: sympathy or indulgence for beliefs or practices differing from or conflicting with one's own

b

: the act of allowing something : toleration

3

: the allowable deviation from a standard

especially : the range of variation permitted in maintaining a specified dimension in machining a piece

4

a(1)

: the capacity of the body to endure or become less responsive to a substance (such as a drug) or a physiological insult especially with repeated use or exposure

developed a tolerance to painkillers

also : the immunological state marked by unresponsiveness to a specific antigen

(2)

: relative capacity of an organism to grow or thrive when subjected to an unfavorable environmental factor

b

: the maximum amount of a pesticide residue that may lawfully remain on or in food

Synonyms

• forbearance
• long-suffering
• patience
• sufferance

Examples of tolerance in a Sentence

a tolerance for other lifestyles

The plants have a high tolerance for heat.

Some patients gradually develop a tolerance for the drug and need to be given a larger dose.

Some patients develop greater tolerance for the drug's effects.

Recent Examples on the Web

Individual responses to fentanyl can vary based on the person’s tolerance to the drug, as well as physical and genetic characteristics. —Deidre McPhillips, CNN, 21 Nov. 2024

This information is being presented without consideration of the investment objectives, risk tolerance, or financial circumstances of any specific investor and might not be suitable for all investors. —Wes Moss, Forbes, 21 Nov. 2024

But saying that, people also seem to have a lot less tolerance for talking to people who are bad actors or are trying to spread this information. —Leah Feiger, WIRED, 21 Nov. 2024

Advertisement World & Nation Inside Club Q: Drag queens, dancing, tolerance shattered by gunfire. —Jesse Bedayn, Los Angeles Times, 19 Nov. 2024

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing tolerance

• cross-tolerance
• self-tolerance
• zero tolerance

Kids Definition

tolerance

noun

tol·​er·​ance ˈtäl(-ə)-rən(t)s 

1

a

: ability to put up with something harmful or unpleasant

b

: the ability to adjust to a food or drug so that its effects are experienced less strongly

2

: sympathy for or acceptance of feelings, habits, or beliefs that are different from one's own

Medical Definition

tolerance

noun

tol·​er·​ance ˈtäl(-ə)-rən(t)s 

1

: the capacity of the body to endure or become less responsive to a substance (as a drug) or a physiological insult especially with repeated use or exposure

developed a tolerance to painkillers

2

: the immunological state marked by unresponsiveness to a specific antigen