spherule

noun

spher·​ule ˈsfir-ül 

ˈsfer-,

-ˌyül 

: a little sphere or spherical body

Word History

First Known Use

1665, in the meaning defined above

Medical Definition

spherule

noun

spher·​ule ˈsfir-ül, ˈsfer-, -ˌyül 

: a thick-walled spherical structure enclosing endospores and occurring in the parasitic form of fungi of the genus Coccidioides

Histopathological examination revealed spherules that were consistent with coccidioides species and focal organizing pneumonia with eosinophilia.

—Holenarasipur R. Vikram et al., The New England Journal of Medicine