solubility

noun

sol·​u·​bil·​i·​ty ˌsäl-yə-ˈbi-lə-tē 

1

: the quality or state of being soluble

2

: the amount of a substance that will dissolve in a given amount of another substance

Examples of solubility in a Sentence

Recent Examples on the Web

The study published in 2022 in Pharmaceutics found that dissolving praziquantel, a poorly water-soluble drug used to treat parasitic worm infections, in cow’s milk increased its solubility. —Paul McClure 13, New Atlas, 13 Feb. 2025

Research has also shown that when poorly water-soluble drugs are combined with human or cow’s milk, digestion of the milk increases drug solubility. —Paul McClure 13, New Atlas, 13 Feb. 2025

But the new tag is cleverly designed to change the solubility of the drug molecule it’s attached to. —Michael Irving, New Atlas, 8 Oct. 2024

Doing both is tricky, so many drugs skip the water problem and focus on oil solubility, requiring IV infusion instead. —Michael Irving, New Atlas, 8 Oct. 2024

Word History

First Known Use

1661, in the meaning defined at sense 1

Rhymes for solubility

• affability
• audibility
• bistability
• capability
• changeability
• contractility
• credibility
• culpability
• disability
• disutility
• durability
• fallibility

Kids Definition

solubility

noun

sol·​u·​bil·​i·​ty ˌsäl-yə-ˈbil-ət-ē 

1

: the quality or state of being soluble

2

: the amount of a substance that will dissolve in a given amount of another substance

Medical Definition

solubility

noun

sol·​u·​bil·​i·​ty ˌsäl-yə-ˈbil-ət-ē 

plural solubilities

1

: the quality or state of being soluble

2

: the amount of a substance that will dissolve in a given amount of another substance and is typically expressed as the number of parts by weight dissolved by 100 parts of solvent at a specified temperature and pressure or as percent by weight or by volume