simvastatin

noun

sim·​va·​stat·​in ˈsim-və-ˌsta-tᵊn  ˌsim-və-ˈsta- 

: a semisynthetic drug C₂₅H₃₈O₅ that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus)

Examples of simvastatin in a Sentence

Recent Examples on the Web

When taken with simvastatin, however, the risk of muscle pain and liver damage increases due to higher blood levels of simvastatin. —Phuoc Anh (anne) Nguyen, Pharmd, Ms, Verywell Health, 18 Dec. 2024

Simvastatin: The dosage of amlodipine needs to be reduced when used in combination with simvastatin, a cholesterol medication (brand name Zocor). —Megan Nunn, Verywell Health, 19 Sep. 2024

Patients can obtain low-dose simvastatin without a prescription, but the medications are placed behind the pharmacy counter and distributed after a pharmacist’s consultation. —Joshua Cohen, Forbes, 2 Mar. 2024

One is called simvastatin, used to manage high cholesterol. —Dina Fine Maron, Scientific American, 17 May 2016

For example, a daily glass of this juice boosts simvastatin and lovastatin by 260% if taken at the same time (American Journal of Medicine, January 2016). —Joe Graedon, M.s., and Teresa Graedon, oregonlive, 27 Feb. 2023

The Pfizer drug, Paxlovid, shouldn’t be used at the same time as certain other drugs, including common ones like the cholesterol-lowering pill simvastatin, also known by the brand Zocor. —Peter Loftus, WSJ, 1 Jan. 2022

The day before Hoffart testified in favor of Texas' new anti-clawback law, a patient was charged a $42.60 copay for a generic version of simvastatin, a statin drug. —Sydney Lupkin, latimes.com, 14 Mar. 2018

The day before Hoffart testified in favor of Texas’s new anti-clawback law, a patient was charged a $42.60 copay for a generic version of simvastatin, a statin drug. —Sydney Lupkin, Washington Post, 13 Mar. 2018

Word History

Etymology

sim- (probably alteration of synthetic) + lovastatin

First Known Use

1987, in the meaning defined above

Medical Definition

simvastatin

noun

sim·​va·​stat·​in ˈsim-və-ˌstat-ᵊn  ˌsim-və-ˈstat- 

: a statin drug C₂₅H₃₈O₅ that inhibits the synthesis of cholesterol, is used orally to lower high levels of cholesterol in the blood, and is derived from a compound produced by a mold of the genus Aspergillus (A. terreus)

Note: Simvastatin is marketed under the trademarks Vytorin and Zocor.