side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The system contains unverified reports of side effects, including from patients, doctors and pharmacists. Annika Kim Constantino, CNBC, 12 Sep. 2025 Federal health officials have said side effects are extremely rare. Lawrence Mower, Miami Herald, 12 Sep. 2025 Amen emphasized that some people may feel more tired at first, but this side effect usually abates. Angelica Stabile, FOXNews.com, 12 Sep. 2025 Temporary discomfort during the exam is the main side effect. Mark Gurarie, Health, 12 Sep. 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 14 Sep. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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