purine

noun

pu·​rine ˈpyu̇r-ˌēn How to pronounce purine (audio)
1
: a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group
2
: a derivative of purine
especially : a base (such as adenine or guanine) that is a constituent of DNA or RNA

Examples of purine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Sardines are also high in purines, a chemical found in fish and other foods that can raise your uric acid levels and increase your risk for gout, Hadley adds. Erica Sweeney, EverydayHealth.com, 25 Aug. 2025 An affinity for water Earlier research showed that the ADSL variation in modern humans makes the enzyme less stable and less effective in its production of purine. Mindy Weisberger, CNN Money, 22 Aug. 2025 Alcohol contains purines, compounds naturally found in certain foods and drinks like seafood and alcohol that your body breaks down into uric acid, which can worsen gout attacks. Jillian Kubala, Rd, Health, 8 Jan. 2025 These findings underscore the nuanced interplay of neurotransmitter synthesis, lipid metabolism, microbial activity, and purine metabolism associated with omnivorous dietary patterns. New Atlas, 28 July 2024

Word History

Etymology

German Purin, from Latin purus pure + New Latin uricus uric (from English uric) + German -in -ine entry 2

First Known Use

1898, in the meaning defined at sense 1

Time Traveler
The first known use of purine was in 1898

Browse Nearby Words

Cite this Entry

“Purine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/purine. Accessed 10 Sep. 2025.

Kids Definition

purine

noun
pu·​rine ˈpyu̇(ə)r-ˌēn How to pronounce purine (audio)
: any of a group of bases including several (as adenine or guanine) that are important parts of DNA and RNA

Medical Definition

purine

noun
pu·​rine ˈpyu̇(ə)r-ˌēn How to pronounce purine (audio)
1
: a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group
2
: a derivative of purine
especially : a base (as adenine or guanine) that is a constituent of DNA or RNA

More from Merriam-Webster on purine

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