psychoactive

adjective

psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv 

: affecting the mind or behavior

psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web

Psychedelic mushrooms and their psychoactive compound psilocybin have the potential to treat people with depression and anxiety, including those unresponsive to other medications or therapy. —Kate Ruder, CBS News, 19 Mar. 2025

Emergency Regulations Ban Hemp With THC The emergency regulations prohibit the sale of consumable hemp products with detectable amounts of THC, the primary psychoactive compound in marijuana, or other intoxicating cannabinoids, and set a limit of five servings per package for such products. —A.j. Herrington, Forbes, 12 Mar. 2025

Delta-8 is a type of tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis. —Rowan Briggs, The Mercury News, 17 Jan. 2025

Some of the hemp products even contain delta-9, a psychoactive compound typically found in cannabis. —Robert McCoppin, Chicago Tribune, 14 Feb. 2025

Word History

First Known Use

1959, in the meaning defined above

Phrases Containing psychoactive

• non-psychoactive

Rhymes for psychoactive

• bioactive
• hyperactive
• interactive
• nonreactive
• overactive
• putrefactive
• retroactive
• unattractive
• unreactive
• vasoactive
• active
• tractive

Kids Definition

psychoactive

adjective

psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv 

: affecting the mind or behavior

psychoactive drugs

Medical Definition

psychoactive

adjective

psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv 

: affecting the mind or behavior

psychoactive drugs

THC is the principal psychoactive ingredient in marijuana