proteome

noun

pro·​te·​ome ˈprō-tē-ˌōm 

: the complement of proteins expressed in a cell, tissue, or organism by a genome

Examples of proteome in a Sentence

Recent Examples on the Web

But even before such dramatic increases in human health span happen, progress toward addressing large subsets of the druggable proteome will deliver a steady flow of amazing new drugs. —Chuck Brooks, Forbes, 22 Oct. 2024

Published today in Nature journals, the Space Omics and Medical Atlas (SOMA) includes studies of the participants’ genomes, microbiomes, transcriptomes (the messenger RNA made from their genes), and proteomes (their panoply of proteins). —science.org, 21 June 2024

De la Fuente’s team decided to speed up their search for antibiotic candidates by looking beyond the human proteome, the full set of proteins expressed by an organism’s genome, to those of extinct organisms. —Cecilia.butini, Vox, 4 June 2024

Proteomics can be a powerful tool when researchers compare the proteomes of individuals from different groups, such as in blood from healthy people versus those with breast cancer. —Danielle Whitham, Discover Magazine, 22 Mar. 2024

This technique is an example of studying a sample’s proteome – all the proteins in a particular cell, organism or species. —Danielle Whitham, Discover Magazine, 22 Mar. 2024

For example, the proteome of saliva — an exhaustive catalog of the proteins present in this fluid — is already available, and it is known that between 20 percent and 30 percent of the saliva proteome overlaps with that of blood. —Matías A. Loewy, Discover Magazine, 25 Mar. 2023

For example, the proteome of saliva—an exhaustive catalog of the proteins present in this fluid—is already available, and it is known that between 20 percent and 30 percent of the saliva proteome overlaps with that of blood. —Smithsonian Magazine, 17 Mar. 2023

Those transcripts are used to make the proteins in our body, naturally known as the proteome. —Elizabeth Preston, Discover Magazine, 30 Mar. 2011

Word History

Etymology

prote(in) + -ome (in genome)

Note: The term was first used in print in Valerie C. Wasinger, et al., "Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium," Electrophoresis, vol. 16, no. 7 (July, 1995), pp. 1090-94. According to Wikipedia (as of 6/30/21), proteome was coined by the Australian geneticist Marc R. Wilkins; see Marc R. Wilkins, et al., "Progress with Proteome Projects: Why All Proteins Expressed by a Genome Should be Identified and How To Do It," Biotechnology and Genetic Engineering Reviews, vol. 13 (1996), pp. 19-50; and Marc R. Wilkins, et al., "From Proteins to Proteomes: Large Scale Protein Identification by Two-Dimensional Electrophoresis and Amino Acid Analysis," Nature Biotechnology, vol. 14, issue 1 (January, 1996), pp. 61-65.

First Known Use

1995, in the meaning defined above

Medical Definition

proteome

noun

pro·​te·​ome ˈprōt-ē-ˌōm 

: the complement of proteins expressed in a cell, tissue, or organism by a genome