progenitor

noun

pro·​gen·​i·​tor prō-ˈje-nə-tər How to pronounce progenitor (audio)
prə-
1
a
: an ancestor in the direct line : forefather
b
: a biologically ancestral form
2
: precursor, originator
progenitors of socialist ideasThe Times Literary Supplement (London)
progenitor cells

Examples of progenitor in a Sentence

the progenitors of modern art wild cats that were the progenitors of the house cat
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
New York is usually considered the antithesis of sprawl and Los Angeles the progenitor of it. Conor Dougherty, New York Times, 10 Apr. 2025 Meanwhile, most Cretaceous avian progenitors appear more birdlike, with short tails ending in a compound bone called a pygostyle. Paul Smaglik, Discover Magazine, 12 Feb. 2025 The company isolated expandable endothelial progenitor cells from the blood of red wolves to make their clones. Emily Mullin, Wired News, 7 Apr. 2025 In this timeless progenitor of low-budget horror cinema, a woman survives a devastating car accident and begins seeing paranormal visions of ghoulish men who pursue her to the ends of the earth and her sanity. Samantha Bergeson, IndieWire, 26 Mar. 2025 See All Example Sentences for progenitor

Word History

Etymology

Middle English progenitour, borrowed from Anglo-French & Latin; Anglo-French, borrowed from Latin prōgenitor "individual from whom a person or family is descended, ancestor," agentive derivative of prōgignere "to produce as offspring, bring into being, give rise to" (from prō- pro- entry 2 + gignere "to bring into being, beget, give birth to"), after genitor "father, parent, originator," going back to Indo-European *ǵenh1- "engender, beget" + *-tor/*-tōr, agent suffix, from which also Greek genétōr "father, begetter, ancestor," Sanskrit janitar-, janitá "father, progenitor" — more at kin entry 1

Note: Alternatively genitor has been explained as a new formation based on genitus, past participle of gignere. The older and still somewhat more attractive view sees genitus as the new formation, based on the perfect genuī or on genitor itself, after the connection with the original verbal adjective (g)nātus (going back to zero-grade *ǵn̥h1-to-) became weakened.

First Known Use

14th century, in the meaning defined at sense 1a

Time Traveler
The first known use of progenitor was in the 14th century

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Cite this Entry

“Progenitor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/progenitor. Accessed 22 May. 2025.

Medical Definition

progenitor

noun
pro·​gen·​i·​tor prō-ˈjen-ət-ər, prə- How to pronounce progenitor (audio)
1
: an ancestor of an individual in a direct line of descent along which some or all of the ancestral genes could theoretically have passed
2
: a biologically ancestral form

More from Merriam-Webster on progenitor

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